황지환 (Hwang, Jihwan)
- POSITION
- Professor
- TEL
- 051-510-2194
- EMAIL
- hwangjh@pusan.ac.kr
- SPHERE
- Microbial Physiology
- OFFICE
- 411
1998 Korea University (B.A.)
2004 Rutgers, The State University of New Jersey (Ph.D.)
2004-2010 Rutgers, The State University of New Jersey, Postdoctoral Fellow
2010-2011 Michigan State University, Research Associate
2012-2012 Chung-Ang University, Research Professor
2012-2016 Pusan National University, Assistant Professor
2016-2021 Pusan National University, Associate Professor
2018 Visiting Scholar, University of Florida, USA.
2021-present Pusan National University, Professor
2004-2005 The New York Academy of Sciences, Member
2013-2014 한국생명과학회, 운영위원
2014-2015 한국미생물학회, 운영위원
2014-2015 한국분자세포생물학회, 정회원
2018-2020 한국미생물학회, 편집위원
2021-present 한국미생물학회, 편집위원
2006. 05. ASM 106th General Meeting, Hwang J and Inouye M.
The tandem GTPase, Der, is essential for the biogenesis of 50S ribosomal subunits in Escherichia coli.
2008. 08. Cold Spring Harbor Laboratory, Molecular Genetics of Bacteria & Phages, Hwang J and Inouye M. A bacterial GAP, YihI regulates a tandemly repeated GTPase, Der in Escherichia coli.
2010. 05. ASM 110th General Meeting, Hwang J and Inouye M. Identification of suppressors for nonsense codon-mediated growth inhibition at low temperature.
2012.10. The 53rd Annual Meeting and International Symposium of Korean Society of Life Science, Hwang, Jihwan, Vladimir Tseitin, Kal Ramnarayan, Mark. D. Shenderovich, and Masayori Inouye. Antibiotics development against an essential GTPase, Der as an auxiliary ribosome assembly protein.
Jihwan Hwang, Masayori Inouye, Sangita Phadtare (2013) Ribosomes: Molecular Structure, Role in Biological Functions and Implications for Genetic Diseases; Translational Apparatus of Microorganisms at Low Temperature. Nova Science Publisher
PUBLICATIONS
1. Onju Ham, Chang Youn Lee, Byeong-Wook Song, Se-Yeon Lee, Ran Kim, Jun-Hee Park, Jiyun Lee, Hyang-Hee Seo, Chae Yoon Lee, Yong-An Chung, Lee-So Maeng, Min Young Lee, Jongmin Kim, Jihwan Hwang, Dong Kyun Woo, Woochul Chang (2014). Upregulation of miR-23b enhances the autologous therapeutic potential for degenerative arthritis by targeting PRKACB in synovial fluid-derived mesenchymal stem cells from patients. Molecules and Cells. 37:449-456
2. Wooseok Song, Se-Hoon Sim, Soonhye Hwang, Jung-Hyun Lee, Yong-Hak Kim, Jeehyeon Bae, Jihwan Hwang*, and Kangseok Lee* (*, co-corresponding author). (2014) Antibiotic stress-induced modulation of the endoribonucleolytic activity of RNase III and RNase G confers resistance of Escherichia coli to aminoglycoside antibiotics. Nucleic Acids Research 42:4669-4681.
3. Young Jeon, Chang Sook Ahn, Hyun Ju Jung, Hunseung Kang, Guen Tae Park, Yeonhee Choi, Jihwan Hwang and Hyun-Sook Pai. (2014) DER containing two consecutive GTP-binding domains plays an essential role in chloroplast ribosomal RNA processing and ribosome biogenesis in higher plants. Journal of Experimental Botany. 65:117-130.
4. Hwang J, Lee K, Phadtare S and Inouye M. (2012) Identification of two DNA helicases UvrD and DinG as suppressors for lethality caused by mutant cspA mRNAs. J. Mol. Microbiol. Biotechnol. 22:135-146. (Editor’s choice for free access)
5. Hwang J, Tseitin V, Ramnarayan K, Shenderovich MD and Inouye M. (2012) Structure-based design and screening of inhibitors for an essential bacterial GTPase, Der. J. Antibiot. 65: 237-243. (Featured article in the issue)
6. Jang J, Lee E, Ryou Y, Lee S, Hwang J, Lee H, Kim J, Kang Y and Kim Y. (2011) Electricity production performance of single- and dual-cathode microbial fuel cells coupled to carbon source and nitrate. Korean J. Microbiol. Biotechnol. 39: 382-386.
7. Hwang J and Inouye M. (2010) A bacterial GAP-like protein, YihI, regulating GTPase of Der, an essential GTP-binding protein in Escherichia coli. J. Mol. Biol. 399: 759-772.
8. Hwang J and Inouye M. (2010) Interaction of an essential E. coli GTPase, Der with 50S ribosome via the KH-like domain. J. Bacteriol. 192: 2277-2283.
9. Hwang J and Inouye M. (2008) RelA functionally suppresses the growth defect caused by a mutation in the G domain of the essential Der protein. J. Bacteriol. 190: 3236-3243.
10. Hwang J and Inouye M. (2006) The tandem GTPase, Der, is essential for the biogenesis of 50S ribosomal subunits in Escherichia coli. Mol. Microbiology 61: 1660-1672.
11. Phadtare S, Hwang J, Severinov K and Inouye M. (2003) CspB and CspL, thermostable cold-shock proteins from Thermotoga maritima. Genes Cells 8: 801-810.
12. Robinson VL, Hwang J, Fox E, Inouye M and Stock AM. (2002) Domain arrangement of Der, a switch protein containing two GTPase domains. Structure 10: 1649-1658.
13. Hwang J and Inouye M. (2001) An essential GTPase, der, containing double GTP-binding domains from Escherichia coli and Thermotoga maritima. J. Biol. Chem. 276: 31415-31421.
14. Yamanaka K*, Hwang J* and Inouye M. (2000) Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima. J. Bacteriol. 182: 7078-7082. (*co-first author)